Inflammation in Chronic Wounds

Inflammation in Chronic Wounds

Non-healing chronic wounds present a major biological, psychological, social, and financial burden on both individual patients and the broader health system. Pathologically extensive inflammation plays a major role in the disruption of the normal healing cascade. The causes of chronic wounds (venous, arterial, pressure, and diabetic ulcers) can be examined through a juxtaposition of normal heal...

Chronic WOUNDS

5 10 No 1 “In a biofilm, planktonic bacteria encase themselves in an extra cellular polymeric substance which adheres to the wound bed.” Wound infection is a complication that often contributes to a wound that is failing to heal (World Union of Wound Healing Societies [WUWHS], 2008). A wound that is infected presents many challenges to clinicians and may have a significant impact on the patient...

Chronic WOUNDS

Bacteria usually exist in one of two states: planktonic, existing as free moving cell in the environment, or sessile, attached to a surface. Bacteria in the environment tend to form aggregates or colonies attached to the surface of non-living or living substrates. These aggregated cells secrete a glue-like substance primarily made of exopolysaccharide and proteins, called extracellular polymeri...

Chronic wounds.

Chronic wounds are a challenge to treat for the clinician. We present a current overview of intrinsic and extrinsic factors in the development chronic nonhealing wounds. Solutions to some of these difficult problems are presented.

Chronic Low-grade Inflammation after Exercise: Controversies